Missouri Layoffs — December 2025

Employers in Missouri recorded 2 WARN Act notices in December 2025, covering approximately 364 workers — marking a sharp increase from November and up 884% versus December 2024. The average filing covered 182 workers, with 1 closure among the notices.

Industry Breakdown

Industry	Notices	Workers
Healthcare	1	213
Manufacturing	1	151

The Healthcare sector accounted for the largest share of job cuts with 213 workers across 1 notice. At the same time, Manufacturing reported 151 workers.

Geographic Hotspots

County	Notices	Workers
Butler	1	213
Sullivan	1	151

Butler absorbed the greatest share of layoffs, accounting for 59% of all affected workers with 213 workers across 1 notices.

City	Notices	Workers
Poplar Bluff	1	213
Milan	1	151

Layoff Type Analysis

Type	Notices	Workers
Layoff	1	213
Closure	1	151

Closures accounted for 41% of affected workers, while the majority of filings were layoffs rather than permanent shutdowns.

Largest Layoffs

Company	City	Workers	Type	Date
Saint Francis Healthcare	Poplar Bluff	213	Layoff	2025-12-18
Simmons Animal Nutrition	Milan	151	Closure	2025-12-04

Leading the list was Saint Francis Healthcare at its Poplar Bluff facility, reporting 213 affected workers. Simmons Animal Nutrition followed with 151 workers.

Trend & Outlook

After a dip last month, layoff activity has ticked back up.

The filings reflect mounting pressure on the Missouri labor market, with activity running above both recent and year-ago benchmarks. The Healthcare sector warrants close attention heading into the next period.

This analysis is based on official WARN Act filings reported by Missouri. The Worker Adjustment and Retraining Notification (WARN) Act requires employers with 100+ employees to provide 60-day advance notice of mass layoffs and plant closings. Data is updated daily by WARN Firehose. View all Missouri WARN notices, browse layoffs by state, or download the full dataset.